BION and NuStim Technology & Application

There are no current research projects with these technologies.

Publications

Loeb, G.E. Neural Prosthetics: A Review of Empirical vs. Systems Engineering Strategies Applied Bionics & Biomechanics, vol. 2018, Article ID 1435030, 17 pages, 2018.

Huang, X., Denprasert, P.M., Zhou, L., Vest, A.N., Kohan, S. and Loeb, G.E. Accelerated life-test methods and results for implantable electronic devices with adhesive encapsulationBiomed. Microdevices 19:46, DOI 10.1007/s10544-017-0189-9, 2017.

Huang, X., Zheng, K., Kohan, S., Denprasert, P.M., Liao, L., Loeb, G.E.  Neurostimulation strategy for stress urinary incontinence, DOI: 10.1109/TNSRE.2017.2679077, 2017.

Sinha, U.K., Villegas, B., Kuo, C., Richmond, F.J., Masood, R., Nelson, N.I., and Loeb, G.E. Safety of Microstimulator During Radiation Therapy – A Preliminary Study on Head and Neck Cancer Patients Journal of Nuclear Medicine & Radiation Therapy, 5:197, DOI: 10.4172/2155-9619.1000197, 2014.

Kim YH, Loeb GE, Peck RA, Singh J, Deshpande S, Baker LL, Bryant JT. A failure analysis of intramuscular rigid implants for muscle contractions. Modern Physics Letters B. 2008 May 10;22(11):791-6.

Kaplan, H.M., Baker, L.L., Rubayi, S. and Loeb, G.E. Preventing ischial pressure ulcers: III. Clinical pilot study of chronic neuromuscular electrical stimulation.Applied Bionics & Biomechanics 8:345-359, 2011.

Kaplan, H.M., Baker, L.L., Davoodi, R., Wong, N.T. and Loeb, G.E. Preventing ischial pressure ulcers: II. Biomechanics. Applied Bionics & Biomechanics 8:333-343, 2011.

Kaplan, H.M. and Loeb, G.E. Preventing ischial pressure ulcers: I. Review of neuromuscular electrical stimulation. Applied Bionics & Biomechanics 8:323-331, 2011.

Kaplan, H.M. and Loeb, G.E. Design and Fabrication of an Injection Tool for Neuromuscular Microstimulators. Annals of Biomedical Engineering, 37(9):1858-1970, 2009.

Zou, Q., Tan, W., Kim, E.S., Loeb, G.E. Single- and Triaxis Piezoelectric-Bimorph Accelerometers. J. of Microelectromechanical Systems. 17(1):45-57, 2008.

Loeb, G.E. and Wills, J. General-Purpose Technology for a General-Purpose Nervous System. ISCAS Conference 2008.

Popovic, D., Baker, L.L and Loeb, G.E. Recruitment and comfort of BION implanted electrical stimulation: Implications for FES applications. IEEE Trans Neural Syst Rehabil Eng, 15(4):577-586, 2007.

Loeb, G.E., Peck, R.A., Singh, J., Kim, Y., Deshpande, S., Baker, L.L. and Bryant, J.T. Mechanical Loading of Rigid Intramuscular Implants. Biomedical Microdevices, 9(6):901-910, 2007.

Tran, W. and Loeb, G.E. Feasibility of Prosthetic posture sensing via injectable electronic modules. IEEE Transactions on Rehabilitation Engineering, 15(2):295-309, 2007.

Sachs, N.A. and Loeb, G.E. Development of a BIONic muscle spindle for prosthetic proprioception. IEEE Transactions on Biomedical Engineering, 54(6):1031-1041, June 2007.

Rodriguez, N., Weissberg, J., and Loeb, G.E. Flexible communication and control protocol for injectable neuromuscular interfaces. IEEE Transactions on Biomedical Circuits and Systems, 1(1):19-27, March 2007.

Loeb,G.E., Richmond,F.J. and Baker,L.L. The BION devices: injectable interfaces with peripheral nerves and muscles. Neurosurg. Focus, 20(5):E2, 2006.

Loeb, G.E. and Davoodi, R. The Functional Reanimation of Paralyzed Limbs. IEEE Eng. Med. Biol. Mag., 24(5):45-51, 2005.

Loeb, G.E. Galvani’s Delayed Legacy: Neuromuscular Electrical Stimulation. Expert Review of Medical Devices, 2(4):379-381, July 2005.

Dupont, A.C., Bagg, S.D., Creasy, J.L., Romano, C. Romano, D., Richmond, F.J.R. and Loeb, G.E. First clinical experience with BION® implants for therapeutic electrical stimulation. Neuromodulation 7:38-47, 2004.

Tran, W. H., Loeb, G. E., Richmond, F. J. R., Ahmed, R., Clark, G. T., & Haberman, P. B. (2004). First subject evaluated with simulated BIONtm treatment in posterior genioglossus to prevent obstructive sleep apnea. Proc. 26th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 26 418.

Tran, W. H., Loeb, G. E., Richmond, F. J. R., Dupont, A. C., Mahutte, K. C., Sassoon, C. S. H., & Dickel, M. J. (2003). Development of Asynchronous, Intralingual electrical stimulation to treat obstruction sleep apnea. Proc. 25th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Cancun, Mexico, September 17-21, 2003.

Weber D.J., Stein R.B., Chan K.M., Loeb G.E., Richmond F.J., Rolf R., James K., Chong S.L., Thompson A.K., and Misiaszek J. Functional electrical stimulation using microstimulators to correct foot drop: a case study. Canadian Journal of Physiology & Pharmacology. 82:784-92, 2004.

Dupont Salter, A.-C., Richmond, F.J.R. and Loeb, G.E. Effects of muscle immobilization at different lengths on tetrodotoxin-induced disuse atrophy. IEEE Trans. Neural Sys. Rehab. Engng 11, 209-217, 2003.

Dupont Salter, A.-C., Richmond, F.J.R. and Loeb, G.E. Prevention of muscle disuse atrophy by low-frequency electrical stimulation in rats. IEEE Trans. Neural Sys. Rehab. Engng 11: 218-226, 2003.

Loeb, G.E. and Richmond, F.J.R. BION implants for therapeutic and functional electrical stimulation. Neural Prostheses for Restoration of Sensory and Motor Function, Chapter 3, p. 75-99, 2001.

Loeb, G. E., Peck, R. A., Moore, W. H. and Hood, K. BION™ system for distributed neural prosthetic interfaces. Medical Engineering and Physics, 23:9-18, 2001.

Singh, K., Richmond, F.J.R. and Loeb, G.E. Recruitment properties of intramuscular and nerve-trunk stimulating electrodes. IEEE-Trans. Rehab. Engng., 8(3):276-285, 2000.

Loeb, G.E. and Richmond, F.J.R. FES or TES: How to start an industry? Proceedings of the 4th Annual Conference of the International Functional Electrical Stimulation Society, Sendai, Japan, 169-172, 1999.

Cameron, T., Richmond, F.J.R. and Loeb, G.E. Effects of regional stimulation using a miniature stimulator implanted in feline posterior biceps femoris. IEEE Trans. Biomed. Engng., 45:1036-1043, 1998.

Cameron, T., Liinamaa, T.L., Loeb, G.E. and Richmond, F.J.R. Long-term biocompatibility of a miniature stimulator implanted in feline hind limb muscles. IEEE Trans. Biomed. Engng., 45:1024-1035, 1998.

Cameron, T., Loeb, G.E., Peck, R.A., Schulman, J.H., Strojnik, P. and Troyk, P.R. Micromodular implants to provide electrical stimulation of paralyzed muscles and limbs. IEEE Trans. Biomed. Engng., 44:781-790, 1997.

Loeb, G.E., Zamin, C.J., Schulman, J.H. and Troyk, P.R. Injectable microstimulator for functional electrical stimulation. Med. & Biol. Engng. and Comput. 29:NS13-NS19, 1991.